13 Jun 2025
Baclofen Uses, Effects, and Safety: Everything You Need to Know
- Caspian Fairholm
- 13 Jun 2025
- Health
Imagine your muscles feel constantly stiff, tight, or even painful—almost impossible to relax, making every movement a challenge. That’s the reality for a lot of Aussies with conditions like multiple sclerosis, spinal cord injuries, or cerebral palsy. But there’s a little white tablet that’s been changing how these folks get by: baclofen. It’s often handed out like a golden ticket to looser, more manageable muscles, but what’s actually going on behind the scenes? Let’s pull back the curtain.
How Baclofen Works in the Body
Baclofen isn’t some trendy new arrival; it’s been around since the 1960s, originally developed for epilepsy but famous now for relaxing muscles. The science bit: it’s a GABA-B receptor agonist, which sounds a bit spooky, but all you need to know is that it mimics a calming chemical in your brain called GABA. When baclofen does its job, it tones down the zap-zap-zap of excited nerve signals shooting through the spinal cord. The result? The constant signal to
