Trihexyphenidyl — Uses, Dosage, Side Effects & Safety Tips

Trihexyphenidyl (often called Artane) is an anticholinergic drug used mostly for Parkinson’s disease symptoms and drug-induced movement problems. If you’re wondering how it helps and whether it’s right for you, this page gives straight answers: when doctors use it, common doses, what side effects to expect, and simple safety tips for taking or buying it.

How trihexyphenidyl works and when it's used

Trihexyphenidyl blocks acetylcholine signals in the brain, which helps rebalance movement control when dopamine is low or blocked. Doctors prescribe it for tremor, muscle stiffness, and drooling in Parkinson’s patients, and to treat dystonia or parkinsonism caused by certain antipsychotic drugs. It’s not a cure — it eases specific symptoms.

Typical adult starting doses are low, for example 1 mg two or three times a day. Doctors usually increase gradually every few days up to a maintenance dose—many people stay on 2–8 mg per day, while some may need up to about 15 mg daily under close supervision. Dosing for children or older adults is different and requires careful monitoring.

Side effects, interactions and safety tips

Expect anticholinergic effects: dry mouth, blurred vision, constipation, and difficulty urinating. Some people feel dizzy or sleepy. Older adults can become confused or more forgetful — that’s a key reason clinicians avoid it if cognition is already an issue. If you have narrow-angle glaucoma, enlarged prostate, severe constipation, or a history of urinary retention, trihexyphenidyl may make those conditions worse.

Watch drug interactions. Combining trihexyphenidyl with other anticholinergic medicines, certain antihistamines, or some antidepressants raises side-effect risk. Alcohol and sedatives can increase drowsiness. Always tell your prescriber about every pill and supplement you take so they can check for problems.

Don’t stop suddenly after long use. Ask your doctor about tapering because abrupt stopping might cause rebound symptoms. If you notice sudden confusion, fast heartbeat, high fever, or severe urinary trouble, seek medical help.

Thinking of buying trihexyphenidyl online? Only use pharmacies that require a prescription and show clear contact details. Avoid sites that sell prescription drugs without asking for a prescription. Look for verified seals, read pharmacy reviews, and compare prices carefully. If a price looks too good or a site won’t provide pharmacist contact, walk away.

Want to talk to your doctor about trihexyphenidyl? Ask about specific benefits for your symptoms, how it fits with other meds, what dose to start, and what side effects to watch for. That short conversation will cut down surprises and help you get the right balance between benefit and risk.